Healthy Sarms steroid Aicar for Bodybuilding Supplement selina@ycgmp.com

Whatsapp:+8618872220826
Skype:selina@ycgmp.com
email:selina@ycgmp.com


Acadesine
Alias: AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Assay: 98%
Apperance: White or off-white powder.
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases

What is AICAR ?

SARM AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK) , a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes . In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.
_________________________________________________________________________________________

Application of AICAR

Exercise improves insulin sensitivity.
a single dose of AICAR leads to an apparent enhancement in whole-body, muscle, and liver insulin action in HF rats that extends beyond the expected time of AMPK activation. Whether altered tissue lipid metabolism mediates AICAR effects on insulin action remains to be determined. the results suggest that pharmacological activation of AMPK may have potential in treating insulin-resistant states and type 2 diabetes

_________________________________________________________________________________________

Function of AICAR

SARM AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown . Adenosine-regulating agents (ARAs) hav e been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.